Review: Recent advances in one-pot multi-component catalytic synthesis of amidoalkyl naphthols

Authors

  • Rajesh Singh Pharmaceutical Chemistry Division, Shivalik College of Pharmacy, (Under Local Govt. Deptt, Punjab) Nangal, Distt-Rupnagar, 140126, Punjab, India
  • Renu Bala Pharmaceutical Chemistry Division, Shivalik College of Pharmacy, (Under Local Govt. Deptt, Punjab) Nangal, Distt-Rupnagar, 140126, Punjab, India
  • Robita Duvedi Pharmaceutical Chemistry Division, Shivalik College of Pharmacy, (Under Local Govt. Deptt, Punjab) Nangal, Distt-Rupnagar, 140126, Punjab, India
  • Sahil Kumar Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India
Abstract:

Amidoalkyl-2-naphthols as synthetic intermediates play an important role in medicinal chemistry due to their remarkable biological and many pharmacological properties. Owing to the versatile biological activities, industrial and synthetic applications of these compounds, introduction of an alternative methodology is urgent in synthetic organic chemistry. Low yield and harsh reaction conditions promoted the researchers for the development of novel green catalysts for the synthesis of amidoalkyl-naphthols. Therefore in the present review, we deal with green catalytic synthesis of amidoalkyl-naphthols. The main purpose of this review is to present a survey of the literature on various heterogenous and homogenous catalysts used for the synthesis of amidoalkyl-naphthols alongwith mechanism of reaction since synthesis of such compounds have not been previously reviewed.

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Journal title

volume 5  issue 3

pages  187- 206

publication date 2015-09-01

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